Eif2ak2 | eukaryotic translation initiation factor 2-alpha kinase 2
Physiological systems
20 / 24 physiological systems tested
3 Significantly impacted by the knock-out
Homeostasis/metabolism Immune system Hematopoietic system
17 No significant impact
4 Not tested
Data collections
Gene metrics:5Significant phenotypes
3Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| increased circulating creatinine level | 1 supporting dataset | Eif2ak2em1(IMPC)Mbp | homozygote | Early adult | 6.93x10-5 | ||
| small spleen | 1 supporting dataset | Eif2ak2em1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| abnormal spleen morphology | 1 supporting dataset | Eif2ak2em1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| increased circulating serum albumin level | 1 supporting dataset | Eif2ak2em1(IMPC)Mbp | homozygote | Early adult | 3.75x10-5 | ||
| increased circulating calcium level | 1 supporting dataset | Eif2ak2em1(IMPC)Mbp | homozygote | Early adult | 3.78x10-6 |
| | | | | | | | | | |
External links
No external links available for Eif2ak2.
All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.
| Eif2ak2em1(IMPC)Mbp | Exon Deletion | | mouse |
| Eif2ak2tm1(NCOM)Mfgc | Reporter-tagged deletion allele (with selection cassette) | | targeting vector ES Cell |
| Eif2ak2tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |
| Eif2ak2tm284228(L1L2_Bact_P) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |