Timm13 | translocase of inner mitochondrial membrane 13

GeneMGI:1353432Synonyms: Tim9, Timm9, +1 more

Physiological systems

21 / 24 physiological systems tested

9 Significantly impacted by the knock-out

 Reproductive system Immune system Endocrine/exocrine gland Growth/size/body region Liver/biliary system Hematopoietic system Behavior/neurological Mortality/aging Renal/urinary system

12 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:9Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

enlarged thymus1 supporting datasetTimm13em1(IMPC)TcpheterozygoteEarly adultN/A * 
embryonic lethality prior to organogenesis1 supporting datasetTimm13em1(IMPC)TcphomozygoteE9.5N/A * 
enlarged kidney1 supporting datasetTimm13em1(IMPC)TcpheterozygoteEarly adultN/A * 
abnormal liver morphology1 supporting datasetTimm13em1(IMPC)TcpheterozygoteEarly adultN/A * 
abnormal seminal vesicle morphology1 supporting datasetTimm13em1(IMPC)TcpheterozygoteEarly adultN/A * 
preweaning lethality, complete penetrance3 supporting datasetsTimm13em1(IMPC)TcphomozygoteEarly adultN/A * 
abnormal spleen morphology1 supporting datasetTimm13em1(IMPC)TcpheterozygoteEarly adultN/A * 
small uterus1 supporting datasetTimm13em1(IMPC)TcpheterozygoteEarly adultN/A * 
abnormal freezing behavior1 supporting datasetTimm13em1(IMPC)TcpheterozygoteEarly adult6.84x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Timm13em1(IMPC)TcpIntra-exon deletionmouse
Timm13tm1(KOMP)MbpReporter-tagged deletion allele (with selection cassette)targeting vector
ES Cell
Timm13tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
Timm13tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell

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