Nr2f1 | nuclear receptor subfamily 2, group F, member 1
Physiological systems
20 / 24 physiological systems tested
5 Significantly impacted by the knock-out
Embryo Growth/size/body region Hearing/vestibular/ear Vision/eye Mortality/aging
15 No significant impact
4 Not tested
Gene metrics:4Significant phenotypes
2Associated diseases
Expression examined in:48Adult tissues
50Embryo tissues
| persistence of hyaloid vascular system | 1 supporting dataset | Nr2f1tm1.1(KOMP)Mbp | heterozygote | Early adult | 5.17x10-5 | ||
| abnormal auditory brainstem response | 1 supporting dataset | Nr2f1tm1.1(KOMP)Mbp | heterozygote | Early adult | 6.21x10-6 | ||
| embryonic growth retardation | 1 supporting dataset | Nr2f1tm1.1(KOMP)Mbp | homozygote | E12.5 | N/A * | ||
| preweaning lethality, complete penetrance | 1 supporting dataset | Nr2f1tm1.1(KOMP)Mbp | homozygote | Early adult | N/A * |
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External links
No external links available for Nr2f1.
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| Nr2f1tm1(KOMP)Mbp | Reporter-tagged deletion allele (with selection cassette) | | targeting vector ES Cell mouse |
| Nr2f1tm1.1(KOMP)Mbp | Reporter-tagged deletion allele (post Cre, with no selection cassette) | | mouse |
| Nr2f1tm445413(Ifitm2_intron_L1L2_GT0_LF2A_LacZ_BetactP_neo) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |