Shroom3 | shroom family member 3

GeneMGI:1351655Synonyms: Shrm, Shrm3, +1 more

Physiological systems

15 / 24 physiological systems tested

8 Significantly impacted by the knock-out

 Embryo Growth/size/body region Limbs/digits/tail Nervous system Digestive/alimentary Vision/eye Craniofacial Mortality/aging

7 No significant impact

9 Not tested

Gene metrics:9Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal body wall morphology1 supporting datasetShroom3em1(IMPC)BayhomozygoteE18.5N/A * 
abnormal tail morphology2 supporting datasetsShroom3em1(IMPC)BayhomozygoteE18.5N/A * 
abnormal facial morphology2 supporting datasetsShroom3em1(IMPC)BayhomozygoteE18.5N/A * 
microphthalmia1 supporting datasetShroom3em1(IMPC)BayhomozygoteE18.5N/A * 
exencephaly1 supporting datasetShroom3em1(IMPC)BayhomozygoteE18.5N/A * 
preweaning lethality, complete penetrance3 supporting datasetsShroom3em1(IMPC)BayhomozygoteEarly adultN/A * 
facial cleft1 supporting datasetShroom3em1(IMPC)BayhomozygoteE18.5N/A * 
protruding tongue1 supporting datasetShroom3em1(IMPC)BayhomozygoteE18.5N/A * 
spina bifida1 supporting datasetShroom3em1(IMPC)BayhomozygoteE18.5N/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Shroom3em1(IMPC)BayExon Deletionmouse
Shroom3tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Shroom3tm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell

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