Abca7 | ATP-binding cassette, sub-family A member 7

GeneMGI:1351646Synonyms: Abc51

Physiological systems

17 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Homeostasis/metabolism Behavior/neurological

15 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

2Associated diseases

Expression examined in:48Adult tissues

25Embryo tissues

Phenotypes

Phy. System:



decreased circulating iron level	1 supporting dataset	Abca7^{tm2b(EUCOMM)Hmgu}	homozygote	Early adult	7.34x10^-8
abnormal sleep behavior	1 supporting dataset	Abca7^{tm2b(EUCOMM)Hmgu}	homozygote	Early adult	5.41x10^-5
increased fasting circulating glucose level	1 supporting dataset	Abca7^{tm2b(EUCOMM)Hmgu}	homozygote	Early adult	1.49x10^-6
decreased circulating glucose level	1 supporting dataset	Abca7^{tm2b(EUCOMM)Hmgu}	homozygote	Early adult	8.53x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Abca7.

Associated images

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Histopathology

There is no histopathology data found for Abca7.

IMPC related publications

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External links

No external links available for Abca7.

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*Abca7^{tm2a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Abca7^{tm2b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Abca7^{tm2e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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