Dguok | deoxyguanosine kinase
Physiological systems
17 / 24 physiological systems tested
5 Significantly impacted by the knock-out
Reproductive system Adipose tissue Growth/size/body region Behavior/neurological Skeleton
12 No significant impact
7 Not tested
Data collections
Gene metrics:9Significant phenotypes
5Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
decreased bone mineral density | 1 supporting dataset | Dguokem1(IMPC)J | homozygote | Early adult | 8.64x10-8 | ||
abnormal locomotor behavior | 1 supporting dataset | Dguokem1(IMPC)J | homozygote | Early adult | 6.99x10-6 | ||
increased total body fat amount | 1 supporting dataset | Dguokem1(IMPC)J | homozygote | Early adult | 6.49x10-6 | ||
increased grip strength | 2 supporting datasets | Dguokem1(IMPC)J | homozygote | Early adult | 1.1x10-21 | ||
increased bone mineral content | 1 supporting dataset | Dguokem1(IMPC)J | homozygote | Early adult | 5.04x10-7 | ||
decreased locomotor activity | 6 supporting datasets | Dguokem1(IMPC)J | homozygote | Early adult | 1.79x10-9 | ||
decreased lean body mass | 1 supporting dataset | Dguokem1(IMPC)J | homozygote | Early adult | 9.49x10-6 | ||
decreased exploration in new environment | 1 supporting dataset | Dguokem1(IMPC)J | homozygote | Early adult | 9.59x10-5 | ||
female infertility | 1 supporting dataset | Dguokem1(IMPC)J | homozygote | Early adult | N/A * |
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External links
No external links available for Dguok.
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Dguokem1(IMPC)J | Exon Deletion | | mouse |
Dguoktm43098(L1L2_gt0) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |