Grm7 | glutamate receptor, metabotropic 7

GeneMGI:1351344Synonyms: 6330570A01Rik, E130018M02Rik, +3 more

Physiological systems

17 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Hematopoietic system Behavior/neurological

15 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:6Significant phenotypes
3Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

limb grasping1 supporting datasetGrm7em1(IMPC)HhomozygoteEarly adult4.68x10-18 
hyperactivity9 supporting datasetsGrm7em1(IMPC)HhomozygoteEarly adult6.09x10-26 
increased grip strength1 supporting datasetGrm7em1(IMPC)HhomozygoteEarly adult2.06x10-5 
increased mean platelet volume1 supporting datasetGrm7em1(IMPC)HhomozygoteEarly adult5.7x10-5 
decreased anxiety-related response1 supporting datasetGrm7em1(IMPC)HhomozygoteEarly adult8.16x10-5 
impaired righting response1 supporting datasetGrm7em1(IMPC)HhomozygoteEarly adult9.31x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Grm7em1(IMPC)HExon Deletionmouse
Grm7em2(IMPC)HExon Deletionmouse
Grm7tm1(EGFP_CreERT2)WtsiReporter-tagged deletion allele (with selection cassette)es cell
Grm7tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
Grm7tm2(EGFP_CreERT2)WtsiReporter-tagged deletion allele (with selection cassette)es cell

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