Ddx24 | DEAD box helicase 24
Physiological systems
22 / 24 physiological systems tested
5 Significantly impacted by the knock-out
Reproductive system Endocrine/exocrine gland Behavior/neurological Mortality/aging Renal/urinary system
17 No significant impact
2 Not tested
Data collections
Gene metrics:8Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
abnormal kidney morphology | 1 supporting dataset | Ddx24em1(IMPC)Mbp | heterozygote | Early adult | N/A * | ||
increased freezing behavior | 1 supporting dataset | Ddx24em1(IMPC)Mbp | heterozygote | Early adult | 6.92x10-5 | ||
abnormal adrenal gland morphology | 1 supporting dataset | Ddx24em1(IMPC)Mbp | heterozygote | Early adult | N/A * | ||
preweaning lethality, complete penetrance | 3 supporting datasets | Ddx24em1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
increased exploration in new environment | 1 supporting dataset | Ddx24em1(IMPC)Mbp | heterozygote | Early adult | 5.38x10-6 | ||
embryonic lethality prior to organogenesis | 1 supporting dataset | Ddx24em1(IMPC)Mbp | homozygote | E9.5 | N/A * | ||
prenatal lethality prior to heart atrial septation | 1 supporting dataset | Ddx24em1(IMPC)Mbp | homozygote | E15.5 | N/A * | ||
abnormal ovary morphology | 1 supporting dataset | Ddx24em1(IMPC)Mbp | heterozygote | Early adult | N/A * |
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External links
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Ddx24em1(IMPC)Mbp | Exon Deletion | | mouse |
Ddx24tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
Ddx24tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |