Pla2g7 | phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)

GeneMGI:1351327Synonyms: PAF acetylhydrolase, PAF-AH

Physiological systems

16 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Homeostasis/metabolism Behavior/neurological

14 No significant impact

8 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:4Significant phenotypes
1Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased circulating bilirubin level1 supporting datasetPla2g7em1(IMPC)JhomozygoteEarly adult4.79x10-6 
increased circulating alkaline phosphatase level1 supporting datasetPla2g7em1(IMPC)JhomozygoteEarly adult7.39x10-5 
decreased startle reflex1 supporting datasetPla2g7em1(IMPC)JhomozygoteEarly adult7.65x10-5 
decreased blood urea nitrogen level1 supporting datasetPla2g7em1(IMPC)JhomozygoteEarly adult9.98x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Pla2g7em1(IMPC)JExon Deletionmouse
Pla2g7tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Pla2g7tm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell

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