Podxl | podocalyxin-like

GeneMGI:1351317Synonyms: Ly102, Pclp1, +3 more

Physiological systems

17 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Vision/eye Hematopoietic system Mortality/aging

14 No significant impact

7 Not tested

Gene metrics:4Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased red blood cell distribution width1 supporting datasetPodxlem1(IMPC)HheterozygoteEarly adult6.93x10-5 
abnormal retina morphology1 supporting datasetPodxlem1(IMPC)HheterozygoteEarly adult4.8x10-6 
preweaning lethality, complete penetrance1 supporting datasetPodxlem1(IMPC)HhomozygoteEarly adultN/A * 
decreased hemoglobin content1 supporting datasetPodxlem1(IMPC)HheterozygoteEarly adult2.18x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Podxlem1(IMPC)HExon Deletionmouse
Podxlem2(IMPC)HExon Deletionmouse
Podxltm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Podxltm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell

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