Pla2g2f | phospholipase A2, group IIF

GeneMGI:1349661Synonyms: mGIIFsPLA2s

Physiological systems

22 / 24 physiological systems tested

7 Significantly impacted by the knock-out

 Reproductive system Endocrine/exocrine gland Growth/size/body region Vision/eye Hematopoietic system Behavior/neurological Cardiovascular system

15 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:9Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

enlarged heart2 supporting datasetsPla2g2fem1(IMPC)CcpczhomozygoteEarly adultN/A * 
increased grip strength1 supporting datasetPla2g2fem1(IMPC)CcpczhomozygoteEarly adult2.55x10-5 
abnormal heart morphology2 supporting datasetsPla2g2fem1(IMPC)CcpczhomozygoteEarly adultN/A * 
small testis1 supporting datasetPla2g2fem1(IMPC)CcpczhomozygoteEarly adultN/A * 
abnormal testis morphology1 supporting datasetPla2g2fem1(IMPC)CcpczhomozygoteEarly adultN/A * 
microphthalmia1 supporting datasetPla2g2fem1(IMPC)CcpczhomozygoteEarly adultN/A * 
decreased body weight1 supporting datasetPla2g2fem1(IMPC)CcpczhomozygoteEarly adult4.93x10-6 
abnormal eye morphology1 supporting datasetPla2g2fem1(IMPC)CcpczhomozygoteEarly adultN/A * 
increased mean platelet volume1 supporting datasetPla2g2fem1(IMPC)CcpczhomozygoteEarly adult4.12x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Order Mouse and ES Cells

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Pla2g2fem1(IMPC)CcpczExon Deletionmouse
Pla2g2ftm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Pla2g2ftm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell
Pla2g2ftm41272(L1L2_gt2)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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