Pla2g2f | phospholipase A2, group IIF

GeneMGI:1349661Synonyms: mGIIFsPLA2s

Physiological systems

22 / 24 physiological systems tested

7 Significantly impacted by the knock-out

Reproductive system Endocrine/exocrine gland Growth/size/body region Vision/eye Hematopoietic system Behavior/neurological Cardiovascular system

15 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:9Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



enlarged heart	2 supporting datasets	Pla2g2f^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
increased grip strength	1 supporting dataset	Pla2g2f^{em1(IMPC)Ccpcz}	homozygote	Early adult	2.55x10^-5
abnormal heart morphology	2 supporting datasets	Pla2g2f^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
small testis	1 supporting dataset	Pla2g2f^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal testis morphology	1 supporting dataset	Pla2g2f^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
microphthalmia	1 supporting dataset	Pla2g2f^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
decreased body weight	1 supporting dataset	Pla2g2f^{em1(IMPC)Ccpcz}	homozygote	Early adult	4.93x10^-6
abnormal eye morphology	1 supporting dataset	Pla2g2f^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
increased mean platelet volume	1 supporting dataset	Pla2g2f^{em1(IMPC)Ccpcz}	homozygote	Early adult	4.12x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Pla2g2f.

Associated images

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Histopathology

There is no histopathology data found for Pla2g2f.

IMPC related publications

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External links

No external links available for Pla2g2f.

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*Pla2g2f^{em1(IMPC)Ccpcz}*	Exon Deletion	‌	mouse
*Pla2g2f^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell
*Pla2g2f^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	es cell
*Pla2g2f^{tm41272(L1L2_gt2)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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