Pla2g2e | phospholipase A2, group IIE

GeneMGI:1349660Synonyms: mGIIEsPLA2s

Physiological systems

18 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Homeostasis/metabolism Hematopoietic system Cardiovascular system

15 No significant impact

6 Not tested

Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:70Adult tissues
0Embryo tissues

Phenotypes

increased circulating alkaline phosphatase level1 supporting datasetPla2g2etm1b(EUCOMM)WtsihomozygoteEarly adult1.49x10-5 
increased red blood cell distribution width1 supporting datasetPla2g2etm1b(EUCOMM)WtsihomozygoteEarly adult2.33x10-8 
increased cardiac stroke volume1 supporting datasetPla2g2etm1b(EUCOMM)WtsihomozygoteEarly adult2.37x10-6 
dilated heart left ventricle1 supporting datasetPla2g2etm1b(EUCOMM)WtsihomozygoteEarly adult9.97x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Pla2g2etm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
mouse
Pla2g2etm1b(EUCOMM)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Pla2g2etm1e(EUCOMM)WtsiTargeted, non-conditional allelees cell

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