Mprip | myosin phosphatase Rho interacting protein
Physiological systems
19 / 24 physiological systems tested
5 Significantly impacted by the knock-out
Homeostasis/metabolism Pigmentation Integument Behavior/neurological Mortality/aging
14 No significant impact
5 Not tested
Data collections
Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| abnormal vocalization | 1 supporting dataset | Mpripem1(IMPC)J | heterozygote | Early adult | 2.42x10-10 | ||
| decreased grip strength | 3 supporting datasets | Mpripem1(IMPC)J | heterozygote | Early adult | 2.73x10-8 | ||
| preweaning lethality, complete penetrance | 1 supporting dataset | Mpripem1(IMPC)J | homozygote | Early adult | N/A * | ||
| abnormal coat/hair pigmentation | 1 supporting dataset | Mpripem1(IMPC)J | heterozygote | Early adult | 4.2x10-12 | ||
| abnormal locomotor behavior | 1 supporting dataset | Mpripem1(IMPC)J | heterozygote | Early adult | 1.5x10-5 | ||
| increased circulating alkaline phosphatase level | 1 supporting dataset | Mpripem1(IMPC)J | heterozygote | Early adult | 1.17x10-5 |
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External links
No external links available for Mprip.
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| Mpripem1(IMPC)J | Exon Deletion | | mouse |
| Mpriptm1e(EUCOMM)Wtsi | Targeted, non-conditional allele | | ES Cell |
| Mpriptm288(L1L2_gt0) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |