Zfp346 | zinc finger protein 346

Physiological systems

17 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Homeostasis/metabolism Mortality/aging

15 No significant impact

7 Not tested

Gene metrics:2Significant phenotypes
0Associated diseases
Expression examined in:48Adult tissues
46Embryo tissues

Phenotypes

increased circulating free fatty acids level1 supporting datasetZfp346tm1.1(KOMP)VlcgheterozygoteEarly adult9.28x10-5 
preweaning lethality, incomplete penetrance1 supporting datasetZfp346tm1.1(KOMP)VlcghomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Zfp346tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
mouse
Zfp346tm1.1(KOMP)VlcgReporter-tagged deletion allele (post Cre, with no selection cassette)mouse
Zfp346tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Zfp346tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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