Sdc2 | syndecan 2

GeneMGI:1349165Synonyms: fibroglycan, 4833414L08Rik, +2 more

Physiological systems

19 / 24 physiological systems tested

6 Significantly impacted by the knock-out

Homeostasis/metabolism Pigmentation Integument Vision/eye Hematopoietic system Cardiovascular system

13 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:7Significant phenotypes

0Associated diseases

Expression examined in:70Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased cardiac output	1 supporting dataset	Sdc2^{tm1b(KOMP)Wtsi}	homozygote	Early adult	1.25x10^-5
decreased red blood cell distribution width	1 supporting dataset	Sdc2^{tm1b(KOMP)Wtsi}	homozygote	Early adult	1.89x10^-5
abnormal lens morphology	2 supporting datasets	Sdc2^{tm1b(KOMP)Wtsi}	homozygote	Early adult	3.07x10^-8
increased circulating triglyceride level	1 supporting dataset	Sdc2^{tm1b(KOMP)Wtsi}	homozygote	Early adult	3.85x10^-7
decreased total retina thickness	1 supporting dataset	Sdc2^{tm1b(KOMP)Wtsi}	homozygote	Early adult	1.85x10^-6
abnormal coat/hair pigmentation	1 supporting dataset	Sdc2^{tm1b(KOMP)Wtsi}	homozygote	Early adult	3.78x10^-8
aorta stenosis	1 supporting dataset	Sdc2^{tm1b(KOMP)Wtsi}	homozygote	Early adult	5.29x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Sdc2.

Associated images

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Histopathology

There is no histopathology data found for Sdc2.

IMPC related publications

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External links

No external links available for Sdc2.

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*Sdc2^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Sdc2^{tm1b(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse

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