Usp5 | ubiquitin specific peptidase 5 (isopeptidase T)

GeneMGI:1347343Synonyms: Ucht

Physiological systems

18 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Immune system Hematopoietic system Mortality/aging

15 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:2Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

preweaning lethality, complete penetrance1 supporting datasetUsp5tm1a(EUCOMM)HmguhomozygoteEarly adultN/A * 
decreased leukocyte cell number1 supporting datasetUsp5tm1a(EUCOMM)HmguheterozygoteEarly adult5.45x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Usp5tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
Usp5tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Usp5tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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