Bdp1 | B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB
Physiological systems
21 / 24 physiological systems tested
5 Significantly impacted by the knock-out
Immune system Growth/size/body region Hematopoietic system Mortality/aging Renal/urinary system
16 No significant impact
3 Not tested
Data collections
Gene metrics:7Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| embryonic lethality prior to organogenesis | 1 supporting dataset | Bdp1em1(IMPC)Tcp | homozygote | E9.5 | N/A * | ||
| increased lymphocyte cell number | 1 supporting dataset | Bdp1em1(IMPC)Tcp | heterozygote | Early adult | 8.3x10-5 | ||
| abnormal spleen morphology | 1 supporting dataset | Bdp1em1(IMPC)Tcp | heterozygote | Early adult | N/A * | ||
| preweaning lethality, complete penetrance | 3 supporting datasets | Bdp1em1(IMPC)Tcp | homozygote | Early adult | N/A * | ||
| prenatal lethality prior to heart atrial septation | 1 supporting dataset | Bdp1em1(IMPC)Tcp | homozygote | E15.5 | N/A * | ||
| decreased neutrophil cell number | 1 supporting dataset | Bdp1em1(IMPC)Tcp | heterozygote | Early adult | 2.14x10-5 | ||
| enlarged urinary bladder | 1 supporting dataset | Bdp1em1(IMPC)Tcp | heterozygote | Early adult | N/A * |
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External links
No external links available for Bdp1.
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| Bdp1em1(IMPC)Tcp | Exon Deletion | | mouse |
| Bdp1tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Bdp1tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |