Vnn3 | vanin 3

Physiological systems

22 / 24 physiological systems tested

10 Significantly impacted by the knock-out

Reproductive system Immune system Endocrine/exocrine gland Integument Adipose tissue Growth/size/body region Muscle Hematopoietic system Cardiovascular system Renal/urinary system

12 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:15Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



small seminal vesicle	1 supporting dataset	Vnn3^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal spleen morphology	1 supporting dataset	Vnn3^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
enlarged uterus	1 supporting dataset	Vnn3^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
decreased total body fat amount	1 supporting dataset	Vnn3^{em1(IMPC)Ccpcz}	homozygote	Early adult	2.14x10^-6
abnormal skeletal muscle morphology	2 supporting datasets	Vnn3^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal seminal vesicle morphology	1 supporting dataset	Vnn3^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
enlarged heart	1 supporting dataset	Vnn3^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
enlarged spleen	1 supporting dataset	Vnn3^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal sinus arrhythmia	1 supporting dataset	Vnn3^{em1(IMPC)Ccpcz}	homozygote	Early adult	5.53x10^-6
abnormal heart morphology	1 supporting dataset	Vnn3^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Vnn3.

Associated images

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Histopathology

There is no histopathology data found for Vnn3.

IMPC related publications

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External links

No external links available for Vnn3.

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*Vnn3^{em1(IMPC)Ccpcz}*	Exon Deletion	‌	mouse
*Vnn3^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	es cell
*Vnn3^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell
*Vnn3^{tm2a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell
*Vnn3^{tm2e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	es cell

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