Plod3 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
Physiological systems
20 / 24 physiological systems tested
6 Significantly impacted by the knock-out
Embryo Growth/size/body region Hearing/vestibular/ear Mortality/aging Cardiovascular system Renal/urinary system
14 No significant impact
4 Not tested
Gene metrics:7Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
29Embryo tissues
| embryonic lethality prior to tooth bud stage | 1 supporting dataset | Plod3tm1.1(KOMP)Wtsi | homozygote | E12.5 | N/A * | ||
| embryonic growth retardation | 1 supporting dataset | Plod3tm1.1(KOMP)Wtsi | homozygote | E9.5 | N/A * | ||
| abnormal embryo size | 1 supporting dataset | Plod3tm1.1(KOMP)Wtsi | homozygote | E9.5 | N/A * | ||
| abnormal urinary bladder morphology | 1 supporting dataset | Plod3tm1.1(KOMP)Wtsi | heterozygote | Early adult | N/A * | ||
| preweaning lethality, complete penetrance | 3 supporting datasets | Plod3tm1.1(KOMP)Wtsi | homozygote | Early adult | N/A * | ||
| abnormal pericardium morphology | 1 supporting dataset | Plod3tm1.1(KOMP)Wtsi | homozygote | E9.5 | N/A * | ||
| abnormal auditory brainstem response | 1 supporting dataset | Plod3tm1.1(KOMP)Wtsi | heterozygote | Early adult | 7.19x10-5 |
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External links
No external links available for Plod3.
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| Plod3tm1(KOMP)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | targeting vector ES Cell mouse |
| Plod3tm1.1(KOMP)Wtsi | Reporter-tagged deletion allele (post Cre, with no selection cassette) | | mouse |
| Plod3tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |