Plod2 | procollagen lysine, 2-oxoglutarate 5-dioxygenase 2

GeneMGI:1347007Synonyms: LH2, lysyl hydroxylase 2, +2 more

Physiological systems

20 / 24 physiological systems tested

6 Significantly impacted by the knock-out

 Pigmentation Integument Embryo Growth/size/body region Behavior/neurological Mortality/aging

14 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:8Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal locomotor behavior1 supporting datasetPlod2em1(IMPC)JheterozygoteLate adult1.99x10-5 
abnormal embryo size1 supporting datasetPlod2em1(IMPC)JheterozygoteE15.5N/A * 
abnormal coat/ hair morphology1 supporting datasetPlod2em1(IMPC)JheterozygoteLate adult2.62x10-6 
abnormal embryo size1 supporting datasetPlod2em1(IMPC)JhomozygoteE12.5N/A * 
impaired righting response1 supporting datasetPlod2em1(IMPC)JheterozygoteLate adult1.02x10-6 
abnormal coat/hair pigmentation1 supporting datasetPlod2em1(IMPC)JheterozygoteLate adult4.37x10-8 
preweaning lethality, complete penetrance1 supporting datasetPlod2em1(IMPC)JhomozygoteEarly adultN/A * 
limb grasping1 supporting datasetPlod2em1(IMPC)JheterozygoteLate adult1.5x10-7 
prenatal lethality1 supporting datasetPlod2em1(IMPC)JhomozygoteE18.5N/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Plod2em1(IMPC)JExon Deletionmouse
Plod2tm294673(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector
Plod2tm82540(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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