Scamp2 | secretory carrier membrane protein 2

GeneMGI:1346518Synonyms: Sc2

Physiological systems

17 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Homeostasis/metabolism Hearing/vestibular/ear Vision/eye Behavior/neurological

13 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:8Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal auditory brainstem response8 supporting datasetsScamp2em1(IMPC)JhomozygoteEarly adult6.67x10-7 
increased circulating total protein level1 supporting datasetScamp2em1(IMPC)JhomozygoteLate adult2.75x10-6 
decreased fasting circulating glucose level1 supporting datasetScamp2em1(IMPC)JhomozygoteEarly adult4.13x10-9 
decreased grip strength1 supporting datasetScamp2em1(IMPC)JhomozygoteLate adult6.13x10-5 
sclerocornea1 supporting datasetScamp2em1(IMPC)JhomozygoteLate adult9.45x10-5 
cataract1 supporting datasetScamp2em1(IMPC)JhomozygoteEarly adult1x10-5 
decreased startle reflex1 supporting datasetScamp2em1(IMPC)JhomozygoteEarly adult4.96x10-7 
abnormal startle reflex1 supporting datasetScamp2em1(IMPC)JhomozygoteLate adult1.94x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Scamp2em1(IMPC)JExon Deletionmouse
Scamp2tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
Scamp2tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Scamp2tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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