Fyb1 | FYN binding protein 1

GeneMGI:1346327Synonyms: B630013F22Rik, Fyb, +2 more

Physiological systems

18 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Homeostasis/metabolism Vision/eye Hematopoietic system

15 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal lens morphology	1 supporting dataset	Fyb1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	1.81x10^-9
cataract	1 supporting dataset	Fyb1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	5.33x10^-9
increased respiratory quotient	1 supporting dataset	Fyb1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	5.23x10^-5
thrombocytopenia	1 supporting dataset	Fyb1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	5.71x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Fyb1.

Associated images

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Histopathology

There is no histopathology data found for Fyb1.

IMPC related publications

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External links

No external links available for Fyb1.

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*Fyb1^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	es cell
*Fyb1^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Fyb1^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse

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