Dlgap1 | DLG associated protein 1

GeneMGI:1346065Synonyms: Sapap1, Gkap, +5 more

Physiological systems

18 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Endocrine/exocrine gland Integument Vision/eye Behavior/neurological

14 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

hyperactivity1 supporting datasetDlgap1em1(IMPC)TcphomozygoteEarly adult9.74x10-7 
microphthalmia1 supporting datasetDlgap1em1(IMPC)TcphomozygoteEarly adultN/A * 
small adrenal glands1 supporting datasetDlgap1em1(IMPC)TcphomozygoteEarly adultN/A * 
abnormal eye morphology1 supporting datasetDlgap1em1(IMPC)TcphomozygoteEarly adultN/A * 
decreased exploration in new environment2 supporting datasetsDlgap1em1(IMPC)TcphomozygoteEarly adult1.75x10-8 
abnormal skin morphology1 supporting datasetDlgap1em1(IMPC)TcphomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Dlgap1em1(IMPC)TcpExon Deletionmouse
Dlgap1tm270970(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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