Mab21l2 | mab-21-like 2

Physiological systems

22 / 24 physiological systems tested

8 Significantly impacted by the knock-out

 Homeostasis/metabolism Embryo Growth/size/body region Nervous system Vision/eye Behavior/neurological Cardiovascular system Mortality/aging

14 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:12Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

no spontaneous movement1 supporting datasetMab21l2em1(IMPC)MbpheterozygoteE18.5N/A * 
abnormal placenta vasculature1 supporting datasetMab21l2em1(IMPC)MbpheterozygoteE15.5N/A * 
microphthalmia1 supporting datasetMab21l2em1(IMPC)MbpheterozygoteE15.5N/A * 
abnormal neural tube morphology1 supporting datasetMab21l2em1(IMPC)MbpheterozygoteE9.5N/A * 
anophthalmia1 supporting datasetMab21l2em1(IMPC)MbpheterozygoteEarly adultN/A * 
abnormal eye morphology1 supporting datasetMab21l2em1(IMPC)MbpheterozygoteEarly adultN/A * 
abnormal placenta morphology1 supporting datasetMab21l2em1(IMPC)MbpheterozygoteE15.5N/A * 
embryonic growth retardation1 supporting datasetMab21l2em1(IMPC)MbpheterozygoteE15.5N/A * 
prenatal lethality prior to heart atrial septation1 supporting datasetMab21l2em1(IMPC)MbphomozygoteE15.5N/A * 
preweaning lethality, complete penetrance3 supporting datasetsMab21l2em1(IMPC)MbphomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Mab21l2em1(IMPC)MbpWhole-gene deletionmouse

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