Clpx | caseinolytic mitochondrial matrix peptidase chaperone subunit

Physiological systems

18 / 24 physiological systems tested

1 Significantly impacted by the knock-out

 Mortality/aging

17 No significant impact

6 Not tested

Gene metrics:2Significant phenotypes
1Associated diseases
Expression examined in:48Adult tissues
25Embryo tissues

Phenotypes

embryonic lethality prior to organogenesis1 supporting datasetClpxtm1.1(KOMP)VlcghomozygoteE9.5N/A * 
preweaning lethality, complete penetrance1 supporting datasetClpxtm1.1(KOMP)VlcghomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Clpxtm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
mouse
Clpxtm1.1(KOMP)VlcgReporter-tagged deletion allele (post Cre, with no selection cassette)mouse
Clpxtm82811(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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