Amfr | autocrine motility factor receptor
Physiological systems
19 / 24 physiological systems tested
4 Significantly impacted by the knock-out
Homeostasis/metabolism Growth/size/body region Behavior/neurological Skeleton
15 No significant impact
5 Not tested
Data collections
Gene metrics:8Significant phenotypes
1Associated diseases
Expression examined in:45Adult tissues
0Embryo tissues
| decreased circulating total protein level | 1 supporting dataset | Amfrtm1a(KOMP)Wtsi | homozygote | Early adult | 1.82x10-7 | ||
| increased lean body mass | 1 supporting dataset | Amfrtm1a(KOMP)Wtsi | homozygote | Early adult | 1x10-5 | ||
| increased bone mineral density | 1 supporting dataset | Amfrtm1a(KOMP)Wtsi | homozygote | Early adult | 5.91x10-7 | ||
| abnormal behavior | 1 supporting dataset | Amfrtm1a(KOMP)Wtsi | homozygote | Early adult | 3.89x10-5 | ||
| decreased circulating cholesterol level | 1 supporting dataset | Amfrtm1a(KOMP)Wtsi | homozygote | Early adult | 6.23x10-6 | ||
| decreased circulating alanine transaminase level | 1 supporting dataset | Amfrtm1a(KOMP)Wtsi | homozygote | Early adult | 9.01x10-7 | ||
| abnormal behavior | 1 supporting dataset | Amfrtm1a(KOMP)Wtsi | heterozygote | Early adult | 1.03x10-5 | ||
| decreased locomotor activity | 1 supporting dataset | Amfrtm1a(KOMP)Wtsi | heterozygote | Early adult | 2.41x10-5 | ||
| decreased lactate dehydrogenase level | 1 supporting dataset | Amfrtm1a(KOMP)Wtsi | homozygote | Early adult | 1.31x10-6 |
| | | | | | | | | | |
External links
No external links available for Amfr.
All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.
| Amfrem1(IMPC)Wtsi | Exon Deletion | | mouse |
| Amfrtm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Amfrtm1e(KOMP)Wtsi | Targeted, non-conditional allele | | ES Cell |