Ik | IK cytokine

GeneMGI:1345142Synonyms: MuRED

Physiological systems

20 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Reproductive system Endocrine/exocrine gland Vision/eye Behavior/neurological Mortality/aging

15 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased grip strength4 supporting datasetsIkem2(IMPC)KmpcheterozygoteLate adult2.19x10-7 
embryonic lethality prior to organogenesis1 supporting datasetIkem2(IMPC)KmpchomozygoteE9.5N/A * 
embryonic lethality prior to tooth bud stage1 supporting datasetIkem2(IMPC)KmpchomozygoteE12.5N/A * 
abnormal cornea morphology1 supporting datasetIkem2(IMPC)KmpcheterozygoteLate adult3.87x10-5 
abnormal seminal vesicle morphology1 supporting datasetIkem2(IMPC)KmpcheterozygoteLate adultN/A * 
preweaning lethality, complete penetrance1 supporting datasetIkem2(IMPC)KmpchomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Ikem2(IMPC)KmpcIndelmouse
Iktm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Iktm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell

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