Ash2l | ASH2 like histone lysine methyltransferase complex subunit

Physiological systems

20 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Integument Mortality/aging

18 No significant impact

4 Not tested

Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:51Adult tissues
62Embryo tissues

Phenotypes

embryonic lethality prior to organogenesis1 supporting datasetAsh2ltm1b(EUCOMM)WtsihomozygoteE9.5N/A * 
abnormal coat appearance1 supporting datasetAsh2ltm1b(EUCOMM)WtsiheterozygoteEarly adult6.87x10-5 
preweaning lethality, complete penetrance3 supporting datasetsAsh2ltm1b(EUCOMM)WtsihomozygoteEarly adultN/A * 
abnormal skin coloration1 supporting datasetAsh2ltm1b(EUCOMM)WtsiheterozygoteEarly adult5.72x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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