Pebp1 | phosphatidylethanolamine binding protein 1

GeneMGI:1344408Synonyms: RKIP, Pbp1, +3 more

Physiological systems

20 / 24 physiological systems tested

10 Significantly impacted by the knock-out

 Reproductive system Immune system Endocrine/exocrine gland Integument Liver/biliary system Hematopoietic system Behavior/neurological Skeleton Cardiovascular system Renal/urinary system

10 No significant impact

4 Not tested

Gene metrics:13Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal heart morphology1 supporting datasetPebp1em1(IMPC)TcphomozygoteLate adultN/A * 
abnormal ovary morphology1 supporting datasetPebp1em1(IMPC)TcphomozygoteLate adultN/A * 
abnormal skin morphology1 supporting datasetPebp1em1(IMPC)TcphomozygoteEarly adultN/A * 
decreased eosinophil cell number1 supporting datasetPebp1em1(IMPC)TcphomozygoteLate adult5.94x10-5 
abnormal seminal vesicle morphology1 supporting datasetPebp1em1(IMPC)TcphomozygoteLate adultN/A * 
abnormal liver morphology1 supporting datasetPebp1em1(IMPC)TcphomozygoteLate adultN/A * 
abnormal gallbladder morphology1 supporting datasetPebp1em1(IMPC)TcphomozygoteLate adultN/A * 
small spleen1 supporting datasetPebp1em1(IMPC)TcphomozygoteLate adultN/A * 
decreased bone mineral density1 supporting datasetPebp1em1(IMPC)TcphomozygoteEarly adult3.41x10-5 
decreased exploration in new environment1 supporting datasetPebp1em1(IMPC)TcphomozygoteLate adult1.09x10-7 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Pebp1em1(IMPC)TcpExon Deletionmouse
Pebp1tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell

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