Grem2 | gremlin 2, DAN family BMP antagonist
Physiological systems
20 / 24 physiological systems tested
2 Significantly impacted by the knock-out
Cardiovascular system Mortality/aging
18 No significant impact
4 Not tested
Data collections
Gene metrics:3Significant phenotypes
1Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
dilated heart left ventricle | 3 supporting datasets | Grem2em1(IMPC)Bay | heterozygote | Early adult | 3.59x10-6 | ||
preweaning lethality, incomplete penetrance | 3 supporting datasets | Grem2em1(IMPC)Bay | homozygote | Early adult | N/A * | ||
increased cardiac stroke volume | 1 supporting dataset | Grem2em1(IMPC)Bay | heterozygote | Early adult | 4.74x10-10 |
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External links
No external links available for Grem2.
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Grem2em1(IMPC)Bay | Exon Deletion | | mouse |
Grem2tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector es cell |
Grem2tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | es cell |