Dlg2 | discs large MAGUK scaffold protein 2

GeneMGI:1344351Synonyms: Dlgh2, LOC382816, +6 more

Physiological systems

20 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Homeostasis/metabolism Growth/size/body region

18 No significant impact

4 Not tested

Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased body weight3 supporting datasetsDlg2tm1DsbhomozygoteEarly adult6.88x10-8 
increased lean body mass1 supporting datasetDlg2tm1DsbhomozygoteEarly adult4.89x10-5 
decreased circulating HDL cholesterol level1 supporting datasetDlg2tm1DsbhomozygoteEarly adult1.24x10-5 
decreased circulating LDL cholesterol level1 supporting datasetDlg2tm1DsbhomozygoteEarly adult5.36x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Dlg2tm1DsbReporter-tagged deletion allele (with selection cassette)ES Cell
Dlg2tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Dlg2tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell
Dlg2tm1e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell
Dlg2tm42053(L1L2_gt1)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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