Rnf216 | ring finger protein 216

GeneMGI:1344349Synonyms: UIP83, F830018F18Rik, +2 more

Physiological systems

17 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Homeostasis/metabolism Reproductive system Immune system Hematopoietic system

13 No significant impact

7 Not tested

Gene metrics:7Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased fasting circulating glucose level1 supporting datasetRnf216tm1b(EUCOMM)WtsihomozygoteEarly adult3.44x10-5 
increased monocyte cell number1 supporting datasetRnf216tm1b(EUCOMM)WtsihomozygoteEarly adult1.18x10-5 
male infertility1 supporting datasetRnf216tm1b(EUCOMM)WtsihomozygoteEarly adultN/A * 
decreased lymphocyte cell number1 supporting datasetRnf216tm1b(EUCOMM)WtsihomozygoteEarly adult8.79x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Rnf216tm1(NCOM)MfgcReporter-tagged deletion allele (with selection cassette)targeting vector
ES Cell
Rnf216tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Rnf216tm1b(EUCOMM)WtsiReporter-tagged deletion allele (with selection cassette)mouse

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