Edar | ectodysplasin-A receptor

GeneMGI:1343498

Physiological systems

21 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Nervous system Mortality/aging

19 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:2Significant phenotypes

5Associated diseases

Expression examined in:42Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



decreased prepulse inhibition	1 supporting dataset	Edar^{tm1b(KOMP)Wtsi}	heterozygote	Early adult	7.73x10^-6
preweaning lethality, incomplete penetrance	2 supporting datasets	Edar^{tm1b(KOMP)Wtsi}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Edar.

Associated images

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Histopathology

There is no histopathology data found for Edar.

IMPC related publications

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External links

No external links available for Edar.

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*Edar^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Edar^{tm1b(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Edar^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell
*Edar^{tm43507(L1L2_st0)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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