Mpdz | multiple PDZ domain crumbs cell polarity complex component
Physiological systems
18 / 24 physiological systems tested
6 Significantly impacted by the knock-out
Homeostasis/metabolism Growth/size/body region Hearing/vestibular/ear Vision/eye Behavior/neurological Cardiovascular system
12 No significant impact
6 Not tested
Data collections
Gene metrics:9Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| increased heart weight | 1 supporting dataset | Mpdzem1(IMPC)J | homozygote | Early adult | 1.16x10-6 | ||
| abnormal auditory brainstem response | 5 supporting datasets | Mpdzem1(IMPC)J | homozygote | Early adult | 3.5x10-12 | ||
| abnormal retina morphology | 1 supporting dataset | Mpdzem1(IMPC)J | homozygote | Early adult | 4.19x10-7 | ||
| abnormal retina blood vessel morphology | 2 supporting datasets | Mpdzem1(IMPC)J | homozygote | Early adult | 2.12x10-19 | ||
| decreased grip strength | 3 supporting datasets | Mpdzem1(IMPC)J | homozygote | Early adult | 1.49x10-8 | ||
| improved glucose tolerance | 1 supporting dataset | Mpdzem1(IMPC)J | homozygote | Early adult | 1.32x10-5 | ||
| decreased startle reflex | 1 supporting dataset | Mpdzem1(IMPC)J | homozygote | Early adult | 8.14x10-6 | ||
| increased circulating potassium level | 1 supporting dataset | Mpdzem1(IMPC)J | homozygote | Early adult | 4.79x10-5 | ||
| abnormal retina vasculature morphology | 1 supporting dataset | Mpdzem1(IMPC)J | homozygote | Early adult | 5.61x10-17 |
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External links
No external links available for Mpdz.
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| Mpdzem1(IMPC)J | Indel | | mouse |