Trip6 | thyroid hormone receptor interactor 6

GeneMGI:1343458

Physiological systems

13 / 24 physiological systems tested

7 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Growth/size/body region Nervous system Hematopoietic system Skeleton Craniofacial

6 No significant impact

11 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

0Associated diseases

Expression examined in:51Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



abnormal cranium morphology	1 supporting dataset	Trip6^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	7.77x10^-8
enlarged spleen	1 supporting dataset	Trip6^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	N/A ^*
increased respiratory quotient	1 supporting dataset	Trip6^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	1.25x10^-5
hydrocephaly	1 supporting dataset	Trip6^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Trip6.

Associated images

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Histopathology

There is no histopathology data found for Trip6.

IMPC related publications

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External links

No external links available for Trip6.

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*Trip6^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Trip6^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse

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