Drg1 | developmentally regulated GTP binding protein 1

GeneMGI:1343297Synonyms: Nedd3

Physiological systems

20 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Endocrine/exocrine gland Integument Digestive/alimentary Hematopoietic system Mortality/aging

15 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

1Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



increased red blood cell distribution width	1 supporting dataset	Drg1^em1(IMPC)Tcp	heterozygote	Early adult	2.12x10^-5
preweaning lethality, incomplete penetrance	3 supporting datasets	Drg1^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*
abnormal salivary gland morphology	1 supporting dataset	Drg1^em1(IMPC)Tcp	heterozygote	Early adult	N/A ^*
abnormal skin morphology	1 supporting dataset	Drg1^em1(IMPC)Tcp	heterozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

Download data as:

‌



‌	‌	‌	‌	‌	‌	‌	‌	‌	‌

* This parameter was manually assessed for significance.

Download data as:

lacZ Expression

No adult expression data available for Drg1.

Associated images

Loading...

Histopathology

There is no histopathology data found for Drg1.

IMPC related publications

Loading...

External links

No external links available for Drg1.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.



*Drg1^em1(IMPC)Tcp*	Exon Deletion	‌	mouse
*Drg1^{tm36(L1L2_gt1)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

My Genes