Snf8 | SNF8, ESCRT-II complex subunit, homolog (S. cerevisiae)

GeneMGI:1343161Synonyms: D11Moh34

Physiological systems

21 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Homeostasis/metabolism Behavior/neurological Mortality/aging

18 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

2Associated diseases

Expression examined in:45Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



decreased circulating free fatty acids level	1 supporting dataset	Snf8^{tm1a(EUCOMM)Wtsi}	heterozygote	Early adult	4.56x10^-6
increased lactate dehydrogenase level	1 supporting dataset	Snf8^{tm1a(EUCOMM)Wtsi}	heterozygote	Early adult	2.57x10^-5
abnormal tail movements	1 supporting dataset	Snf8^{tm1a(EUCOMM)Wtsi}	heterozygote	Early adult	4.17x10^-5
preweaning lethality, complete penetrance	1 supporting dataset	Snf8^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Snf8.

Associated images

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Histopathology

There is no histopathology data found for Snf8.

IMPC related publications

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External links

No external links available for Snf8.

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*Snf8^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	es cell
*Snf8^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell
*Snf8^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Snf8^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	es cell
*Snf8^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	es cell
*Snf8^{tm2a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell
*Snf8^{tm76(L1L2_gt0_Del_LacZ)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector
*Snf8^{tm76(pL1L2_GT0_DelLacZ_bsd)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector
*Snf8^{tm76(pL1L2_frt15_BetactinBSD_frt14_neo_Rox)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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