Robo3 | roundabout guidance receptor 3

GeneMGI:1343102Synonyms: Robo3b, Rig-1, +3 more

Physiological systems

18 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Homeostasis/metabolism Growth/size/body region Vision/eye Mortality/aging Cardiovascular system

13 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



increased heart weight	1 supporting dataset	Robo3^em1(IMPC)H	heterozygote	Early adult	1.69x10^-5
increased circulating bilirubin level	1 supporting dataset	Robo3^em1(IMPC)H	heterozygote	Early adult	2.52x10^-5
abnormal retina morphology	1 supporting dataset	Robo3^em1(IMPC)H	heterozygote	Early adult	2.47x10^-11
preweaning lethality, complete penetrance	1 supporting dataset	Robo3^em1(IMPC)H	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Robo3.

Associated images

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Histopathology

There is no histopathology data found for Robo3.

IMPC related publications

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External links

No external links available for Robo3.

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*Robo3^em1(IMPC)H*	Intra-exon deletion	‌	mouse
*Robo3^{tm48572(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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