Aif1 | allograft inflammatory factor 1

GeneMGI:1343098Synonyms: Iba1, D17H6S50E, +1 more

Physiological systems

19 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Homeostasis/metabolism Growth/size/body region Nervous system Vision/eye Cardiovascular system

14 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:7Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased lean body mass	2 supporting datasets	Aif1^{tm1.1(KOMP)Wtsi}	homozygote	Early adult	9.38x10^-6
abnormal lens morphology	2 supporting datasets	Aif1^{tm1.1(KOMP)Wtsi}	homozygote	Early adult	1.33x10^-6
abnormal optic disk morphology	1 supporting dataset	Aif1^{tm1.1(KOMP)Wtsi}	homozygote	Early adult	9.91x10^-6
abnormal vitreous body morphology	1 supporting dataset	Aif1^{tm1.1(KOMP)Wtsi}	homozygote	Early adult	1.22x10^-5
decreased blood urea nitrogen level	1 supporting dataset	Aif1^{tm1.1(KOMP)Wtsi}	homozygote	Early adult	1.23x10^-8
abnormal retina morphology	1 supporting dataset	Aif1^{tm1.1(KOMP)Wtsi}	homozygote	Early adult	1.65x10^-5
abnormal retina blood vessel morphology	1 supporting dataset	Aif1^{tm1.1(KOMP)Wtsi}	homozygote	Early adult	1.84x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Aif1.

Associated images

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Histopathology

There is no histopathology data found for Aif1.

IMPC related publications

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External links

No external links available for Aif1.

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*Aif1^{tm1(EGFP/cre/ERT2)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell mouse
*Aif1^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell
*Aif1^{tm1(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	targeting vector ES Cell mouse
*Aif1^{tm1.1(KOMP)Wtsi}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	mouse

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