Hdac3 | histone deacetylase 3
GeneMGI:1343091
Physiological systems
20 / 24 physiological systems tested
3 Significantly impacted by the knock-out
Homeostasis/metabolism Hematopoietic system Mortality/aging
17 No significant impact
4 Not tested
Data collections
Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:45Adult tissues
0Embryo tissues
| decreased erythrocyte cell number | 1 supporting dataset | Hdac3tm1a(EUCOMM)Wtsi | heterozygote | Early adult | 1.84x10-5 | ||
| preweaning lethality, complete penetrance | 2 supporting datasets | Hdac3tm1a(EUCOMM)Wtsi | homozygote | Early adult | N/A * | ||
| decreased hematocrit | 1 supporting dataset | Hdac3tm1a(EUCOMM)Wtsi | heterozygote | Early adult | 1.53x10-7 | ||
| increased circulating LDL cholesterol level | 1 supporting dataset | Hdac3tm1a(EUCOMM)Wtsi | heterozygote | Early adult | 2.37x10-7 | ||
| decreased hemoglobin content | 1 supporting dataset | Hdac3tm1a(EUCOMM)Wtsi | heterozygote | Early adult | 1.27x10-5 |
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External links
No external links available for Hdac3.
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| Hdac3tm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | ES Cell |
| Hdac3tm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |