Unc13b | unc-13 homolog B

GeneMGI:1342278Synonyms: Munc13-2, Unc13h2

Physiological systems

21 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Reproductive system Endocrine/exocrine gland Mortality/aging

18 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

0Associated diseases

Expression examined in:73Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



preweaning lethality, incomplete penetrance	3 supporting datasets	Unc13b^{tm1b(KOMP)Wtsi}	homozygote	Early adult	N/A ^*
small testis	1 supporting dataset	Unc13b^{tm1b(KOMP)Wtsi}	heterozygote	Early adult	N/A ^*
abnormal testis morphology	1 supporting dataset	Unc13b^{tm1b(KOMP)Wtsi}	heterozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Unc13b.

Associated images

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Histopathology

There is no histopathology data found for Unc13b.

IMPC related publications

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External links

No external links available for Unc13b.

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*Unc13b^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Unc13b^{tm1b(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Unc13b^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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