Slc25a15 | solute carrier family 25 (mitochondrial carrier ornithine transporter), member 15

GeneMGI:1342274Synonyms: D630044L02Rik, Ornt1

Physiological systems

20 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Adipose tissue Behavior/neurological Mortality/aging Renal/urinary system

16 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:4Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased total body fat amount1 supporting datasetSlc25a15tm1b(EUCOMM)HmguheterozygoteEarly adult1.57x10-6 
abnormal kidney morphology2 supporting datasetsSlc25a15tm1b(EUCOMM)HmguheterozygoteEarly adultN/A * 
decreased exploration in new environment1 supporting datasetSlc25a15tm1b(EUCOMM)HmguheterozygoteEarly adult1.74x10-15 
preweaning lethality, complete penetrance1 supporting datasetSlc25a15tm1b(EUCOMM)HmguhomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Slc25a15tm1(NCOM)MfgcReporter-tagged deletion allele (with selection cassette)targeting vector
ES Cell
Slc25a15tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Slc25a15tm1b(EUCOMM)HmguReporter-tagged deletion allele (with selection cassette)mouse
Slc25a15tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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