Zim1 | zinc finger, imprinted 1

Physiological systems

22 / 24 physiological systems tested

1 Significantly impacted by the knock-out

 Respiratory system

21 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased lung compliance1 supporting datasetZim1em1(IMPC)CcpczhomozygoteEarly adult3.44x10-5 
increased lung elastance3 supporting datasetsZim1em1(IMPC)CcpczhomozygoteEarly adult9.92x10-7 
increased lung tissue damping1 supporting datasetZim1em1(IMPC)CcpczhomozygoteEarly adult2.85x10-9 
abnormal inspiratory capacity1 supporting datasetZim1em1(IMPC)CcpczhomozygoteEarly adult2.16x10-5 
increased airway resistance1 supporting datasetZim1em1(IMPC)CcpczhomozygoteEarly adult8.06x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Zim1em1(IMPC)CcpczExon Deletionmouse
Zim1tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
Zim1tm1e(EUCOMM)HmguTargeted, non-conditional allelees cell

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