Cnga3 | cyclic nucleotide gated channel alpha 3

GeneMGI:1341818Synonyms: CNG3

Physiological systems

21 / 24 physiological systems tested

7 Significantly impacted by the knock-out

 Homeostasis/metabolism Reproductive system Immune system Growth/size/body region Hematopoietic system Mortality/aging Renal/urinary system

14 No significant impact

3 Not tested

Gene metrics:6Significant phenotypes
3Associated diseases
Expression examined in:73Adult tissues
0Embryo tissues

Phenotypes

preweaning lethality, incomplete penetrance1 supporting datasetCnga3tm1.1(KOMP)VlcghomozygoteEarly adultN/A * 
increased circulating alanine transaminase level1 supporting datasetCnga3tm1.1(KOMP)VlcghomozygoteEarly adult1.09x10-9 
enlarged spleen1 supporting datasetCnga3tm1.1(KOMP)VlcgheterozygoteEarly adultN/A * 
decreased body length1 supporting datasetCnga3tm1.1(KOMP)VlcghomozygoteEarly adult4.33x10-7 
abnormal kidney morphology1 supporting datasetCnga3tm1.1(KOMP)VlcghomozygoteEarly adultN/A * 
enlarged uterus1 supporting datasetCnga3tm1.1(KOMP)VlcgheterozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
Download data as:  










* This parameter was manually assessed for significance.
Download data as:  

lacZ Expression

Associated images

Loading...

Histopathology

IMPC related publications

Loading...

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.

Cnga3tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
mouse
Cnga3tm1.1(KOMP)VlcgReporter-tagged deletion allele (post Cre, with no selection cassette)mouse

The IMPC Newsletter

Get highlights of the most important data releases, news and events, delivered straight to your email inbox

Subscribe to newsletter