Cnga3 | cyclic nucleotide gated channel alpha 3

GeneMGI:1341818Synonyms: CNG3

Physiological systems

21 / 24 physiological systems tested

7 Significantly impacted by the knock-out

Homeostasis/metabolism Reproductive system Immune system Growth/size/body region Hematopoietic system Mortality/aging Renal/urinary system

14 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:6Significant phenotypes

3Associated diseases

Expression examined in:73Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



preweaning lethality, incomplete penetrance	1 supporting dataset	Cnga3^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	N/A ^*
increased circulating alanine transaminase level	1 supporting dataset	Cnga3^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	1.09x10^-9
enlarged spleen	1 supporting dataset	Cnga3^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	N/A ^*
decreased body length	1 supporting dataset	Cnga3^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	4.33x10^-7
abnormal kidney morphology	1 supporting dataset	Cnga3^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	N/A ^*
enlarged uterus	1 supporting dataset	Cnga3^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* Does not have a P-value assigned because it was manually marked as significant.

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lacZ Expression

No adult expression data available for Cnga3.

Associated images

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Histopathology

There is no histopathology data found for Cnga3.

IMPC related publications

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External links

No external links available for Cnga3.

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*Cnga3^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	es cell mouse
*Cnga3^{tm1.1(KOMP)Vlcg}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	mouse

My Genes