Ndrg1 | N-myc downstream regulated gene 1
Physiological systems
17 / 24 physiological systems tested
5 Significantly impacted by the knock-out
Homeostasis/metabolism Nervous system Behavior/neurological Skeleton Cardiovascular system
12 No significant impact
7 Not tested
Data collections
Gene metrics:8Significant phenotypes
2Associated diseases
Expression examined in:73Adult tissues
0Embryo tissues
| decreased grip strength | 2 supporting datasets | Ndrg1tm2b(KOMP)Wtsi | homozygote | Early adult | 8.58x10-21 | ||
| decreased prepulse inhibition | 2 supporting datasets | Ndrg1tm2b(KOMP)Wtsi | homozygote | Early adult | 5.8x10-5 | ||
| abnormal gait | 1 supporting dataset | Ndrg1tm2b(KOMP)Wtsi | homozygote | Early adult | 2.09x10-18 | ||
| tremors | 1 supporting dataset | Ndrg1tm2b(KOMP)Wtsi | homozygote | Early adult | 1.44x10-13 | ||
| decreased fasting circulating glucose level | 1 supporting dataset | Ndrg1tm2b(KOMP)Wtsi | homozygote | Early adult | 8.88x10-6 | ||
| increased circulating phosphate level | 1 supporting dataset | Ndrg1tm2b(KOMP)Wtsi | homozygote | Early adult | 9.93x10-5 | ||
| prolonged RR interval | 1 supporting dataset | Ndrg1tm2b(KOMP)Wtsi | homozygote | Early adult | 4.13x10-5 | ||
| decreased bone mineral density | 1 supporting dataset | Ndrg1tm2b(KOMP)Wtsi | homozygote | Early adult | 2.75x10-5 |
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External links
No external links available for Ndrg1.
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| Ndrg1tm1e(KOMP)Wtsi | Targeted, non-conditional allele | | ES Cell |
| Ndrg1tm2a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Ndrg1tm2b(KOMP)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Ndrg1tm2e(KOMP)Wtsi | Targeted, non-conditional allele | | ES Cell |