Kcnh3 | potassium voltage-gated channel, subfamily H (eag-related), member 3

GeneMGI:1341723Synonyms: Elk2, C030044P22Rik, +2 more

Physiological systems

17 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Homeostasis/metabolism Vision/eye Hematopoietic system Behavior/neurological

13 No significant impact

7 Not tested

Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:52Adult tissues
50Embryo tissues

Phenotypes

increased fasting circulating glucose level1 supporting datasetKcnh3tm1.1(KOMP)VlcghomozygoteEarly adult3.44x10-6 
increased hemoglobin content1 supporting datasetKcnh3tm1.1(KOMP)VlcghomozygoteEarly adult6.08x10-5 
increased circulating free fatty acids level1 supporting datasetKcnh3tm1.1(KOMP)VlcgheterozygoteEarly adult5.06x10-5 
abnormal retina morphology1 supporting datasetKcnh3tm1.1(KOMP)VlcghomozygoteEarly adult2.79x10-5 
abnormal retina morphology1 supporting datasetKcnh3tm1.1(KOMP)VlcgheterozygoteEarly adult7.58x10-6 
hyperactivity1 supporting datasetKcnh3tm1.1(KOMP)VlcghomozygoteEarly adult2.38x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Kcnh3tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
mouse
Kcnh3tm1.1(KOMP)VlcgReporter-tagged deletion allele (post Cre, with no selection cassette)mouse
Kcnh3tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Kcnh3tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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