Gldc | glycine decarboxylase

GeneMGI:1341155Synonyms: D030049L12Rik, D19Wsu57e, +1 more

Physiological systems

17 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Skeleton Mortality/aging

15 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:2Significant phenotypes

4Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



abnormal vertebral arch morphology	1 supporting dataset	Gldc^{tm1a(EUCOMM)Wtsi}	heterozygote	Early adult	2.29x10^-5
preweaning lethality, complete penetrance	1 supporting dataset	Gldc^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Gldc.

Associated images

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Histopathology

There is no histopathology data found for Gldc.

IMPC related publications

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External links

No external links available for Gldc.

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*Gldc^em1H*	Point Mutation	‌	mouse
*Gldc^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Gldc^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	es cell

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