Gldc | glycine decarboxylase

GeneMGI:1341155Synonyms: D030049L12Rik, D19Wsu57e, +1 more

Physiological systems

17 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Skeleton Mortality/aging

15 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:2Significant phenotypes
4Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal vertebral arch morphology1 supporting datasetGldctm1a(EUCOMM)WtsiheterozygoteEarly adult2.29x10-5 
preweaning lethality, complete penetrance1 supporting datasetGldctm1a(EUCOMM)WtsihomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Gldcem1HPoint Mutationmouse
Gldctm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Gldctm1e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell

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