Sema4f | sema domain, immunoglobulin domain (Ig), TM domain, and short cytoplasmic domain

GeneMGI:1340055Synonyms: Sema W

Physiological systems

17 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Immune system Hematopoietic system Skeleton

14 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:3Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased bone mineral density1 supporting datasetSema4fem1(IMPC)JhomozygoteEarly adult7.24x10-5 
decreased leukocyte cell number1 supporting datasetSema4fem1(IMPC)JhomozygoteEarly adult6.18x10-5 
decreased bone mineral content1 supporting datasetSema4fem1(IMPC)JhomozygoteEarly adult9.89x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Order Mouse and ES Cells

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Sema4fem1(IMPC)JExon Deletionmouse
Sema4ftm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
Sema4ftm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Sema4ftm1e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell
Sema4ftm2a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Sema4ftm2e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell
Sema4ftm40372(L1L2_st0)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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