Cth | cystathionine gamma lyase

GeneMGI:1339968Synonyms: 0610010I13Rik, CSE

Physiological systems

19 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Vision/eye Behavior/neurological Cardiovascular system

16 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:6Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal retina blood vessel morphology1 supporting datasetCthtm1b(EUCOMM)HmguhomozygoteEarly adult2.77x10-5 
persistence of hyaloid vascular system1 supporting datasetCthtm1b(EUCOMM)HmguhomozygoteEarly adult2.59x10-5 
abnormal retina morphology1 supporting datasetCthtm1b(EUCOMM)HmguhomozygoteEarly adult7.76x10-8 
decreased exploration in new environment1 supporting datasetCthtm1b(EUCOMM)HmguhomozygoteEarly adult9.62x10-5 
abnormal lens morphology1 supporting datasetCthtm1b(EUCOMM)HmguhomozygoteEarly adult6.04x10-8 
abnormal retina vasculature morphology1 supporting datasetCthtm1b(EUCOMM)HmguhomozygoteEarly adult3.33x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Cthtm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
mouse
Cthtm1b(EUCOMM)HmguReporter-tagged deletion allele (with selection cassette)mouse
Cthtm1e(EUCOMM)HmguTargeted, non-conditional allelees cell

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