P2rx7 | purinergic receptor P2X, ligand-gated ion channel, 7

GeneMGI:1339957Synonyms: P2X(7), P2X7R, +1 more

Physiological systems

20 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Homeostasis/metabolism Vision/eye

18 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

1Associated diseases

Expression examined in:70Adult tissues

0Embryo tissues

Phenotypes

Allele:

Phy. System:



decreased circulating glycerol level	1 supporting dataset	P2rx7^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	2.41x10^-5
abnormal lens morphology	1 supporting dataset	P2rx7^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	4.44x10^-5
cataract	1 supporting dataset	P2rx7^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	1.41x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

Download data as:

‌



‌	‌	‌	‌	‌	‌	‌	‌	‌	‌

* This parameter was manually assessed for significance.

Download data as:

lacZ Expression

No adult expression data available for P2rx7.

Associated images

Loading...

Histopathology

There is no histopathology data found for P2rx7.

IMPC related publications

Loading...

External links

No external links available for P2rx7.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.



*P2rx7^{tm1(EGFP_CreERT2)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	es cell mouse
*P2rx7^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	es cell
*P2rx7^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*P2rx7^{tm1b(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*P2rx7^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	es cell

My Genes